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System and method for multidimensional evaluation

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专利名称:System and method for multidimensional

evaluation of combinations of compositions

发明人:Grant Zimmermann,Raymond A.

Molnar,Joseph Lehar,Jason Fong,Curtis T.Keith,George Serbedzija,Margaret S.Lee,Edward R. Jost-Price,Nicole Hurst,AlexisBorisy,Michael A. Foley,Brent Stockwell

申请号:US10863592申请日:20040607

公开号:US200402532A1公开日:20041216

摘要:Embodiments of the invention are directed toward methods and devices forconstructing assay arrays including a combination of constituent compositions fromconstituent arrays. The combined compositions are evaluated, in some embodiments ofthe invention, to identify combinations with a combination effect. Other embodiments ofthe invention are directed toward constructing constituent arrays in various

configurations to facilitate the production of assay arrays. Such embodiments include:constructing constituent arrays and assay arrays with corresponding composition andassay control sets; constructing constituent arrays with a unique set of origin locationsand corresponding sets of derivative locations; varying the concentrations utilized for aconstituent composition; and composing assay arrays corresponding to a virtual sparseassay array. Other embodiments of the invention are directed towards systems andmethod of evaluating the activity of combined compositions in an assay array.

申请人:ZIMMERMANN GRANT,MOLNAR RAYMOND A.,LEHAR JOSEPH,FONGJASON,KEITH CURTIS T.,SERBEDZIJA GEORGE,LEE MARGARET S.,JOST-PRICE EDWARDR.,HURST NICOLE,BORISY ALEXIS,FOLEY MICHAEL A.,STOCKWELL BRENT

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