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PROCESSES FOR DETERMINING THE BIOLOGICAL ACTIVITY

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专利名称:PROCESSES FOR DETERMINING THE

BIOLOGICAL ACTIVITY OF EPIDERMALGROWTH FACTOR RECEPTOR TYROSINEKINASE INHIBITORS

发明人:FÜRST, Peter,GROSSENBACHER, Rita申请号:EP01271450.7申请日:20011218公开号:EP1346062A1公开日:20030924

摘要:The present invention relates to processes for determining the biologicalactivity of compounds that inhibit the tyrosine kinase activity of the Epidermal GrowthFactor Receptor (EGFR) aqnd to the use of transcription or translation products of genesthe expression levels of which correlate with the biological activity of an EGFR tyrosinekinase inhibitor for determining the biological activity of such an EGFR tyrosine kinaseinhibitor.

申请人:Novartis AG,Novartis Pharma GmbH

地址:Lichtstrasse 35 4056 Basel CH,Brunner Strasse 59 1235 Vienna AT

国籍:CH,AT

代理机构:Grubb, Philip William

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