专利内容由知识产权出版社提供
专利名称：DIBENZO A.D CYCLOHEPTENE DERIVATIVES发明人：TETSUTARO HAYASAKA,KUNIRO
SAITO,SEN-ICHI NARITA,TAKAOGOTO,SHIN-ICHI YAMADA,TERUOSAITO,KAZUYOSHI OKUTANI
申请号：AU6268680申请日：19800924公开号：AU534186B2公开日：19840112
摘要：Novel compounds, dibenzo[a,d]cycloheptene derivatives, of the generalformula (I) wherein R1 represents a hydrogen atom, a halogen atom or a lower alkylgroup, R2 and R3 each represent a hydrogen atom or a lower alkyl group, and Zrepresents a group of the formula These novel compounds are useful as non-steroidalanti-inflammatory agents free from gastrointestinal lesions. The compounds of formula(I) can be prepared, for example, by cyclizing a compound of the general formula (II)wherein R1 and R2 are as defined above, X represents a hydroxyl group or a halogenatom, one Y represents a group of the formula -CH2COX and the other Y represents ahydrogen atom; optionally hydrolyzing the cyclized product; and optionally esterifyingthe product, and/or etherifying its enol group.
申请人：TOA EIYO KAGAKU KOGYO CO. LTD.
更多信息请下载全文后查看
