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专利名称：Thiazole derivatives and process for the
preparation thereof
发明人：Antonio B. Vinas申请号：US07/356014申请日：190523公开号：US049566A公开日：19900911
摘要：Thiazole derivatives of the general formula where: ##STR1## X is an anion ofpharmaceutically acceptable acids; a is an integer from 1 to 5;
b is an integer from 1 to 7;
c is 0 or an integer from 1 to 4; and
d is 2a-c for monovalent acid anions, is a-c for divalent acid anions, and is 0 or 2 whenc=0.< P>
The process for the preparation of the above derivatives is based on reacting N-methyl-N'-2-((2-(dimethylaminomethyl)- 4-thiazolyl) methylthio)ethyl)-2-nitro-1,1-ethylenediamine of formula II with an X anion containing zinc compound or an organozinc.
申请人：LABORATORIOS VINAS, S. A.
代理机构：Dressler, Goldsmith, Shore, Sutker & Milnamow, Ltd.
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