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CEBPalpha gene targeting constructs and uses ther

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专利名称:C/EBPalpha gene targeting constructs and

uses thereof

发明人:Nai-dy Wang申请号:US10703224申请日:20031106

公开号:US20050100924A1公开日:20050512

摘要:A DNA construct for the expression of a functional mammalian

C/EBPαcomprising the following components: (i) a first region having homology with anendogenous tumor-specific promoter gene sequence of a gene locus (ii) a DNA moleculeencoding the C/EBPα; and (iii) a second region having homology with a region within thegene locus. The DNA construct is used for the preparation of non-human knock-inanimals.

申请人:Nai-dy Wang

地址:Singapore SG

国籍:SG

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