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专利名称：Nitroderivatives of polysaccharides发明人：Francesca Benedini,Benito Casu,Piero Del
Soldato,Paolo Gresele,Annamaria
Naggi,Giangiacomo Torri,Simona Venturini
申请号：US10362811申请日：20010810公开号：US07005508B2公开日：20060228
摘要：The present invention provides a new class of compounds presenting a highcompatibility with tissues and organic fluids. Such new compounds are polysaccharidesessentially formed of units of uronic acid and/or hexosamine, containing nitro groups —ONOcovalently bonded to the saccharide structure. Preferably, the polysaccharidesaccording to the invention are prevalently formed of disaccharide repeating units formedof uronic acid and hexosamine. These compounds, in psychological conditions, selectivelyrelease NO, allowing a reduction in the amount of NO needed to achieve a determinedtherapeutical effect. This result has been achieved by functionalizing polysaccharidesessentially formed of units of uronic acid and/or hexosamine, with subsituents containinga ONO2 ? group.
申请人：Francesca Benedini,Benito Casu,Piero Del Soldato,Paolo Gresele,AnnamariaNaggi,Giangiacomo Torri,Simona Venturini
地址：Milan IT,Milan IT,Monza IT,Perugia IT,Legnano IT,Milan IT,Seveso IT
国籍：IT,IT,IT,IT,IT,IT,IT
代理机构：Yankwich & Associates, P.C.
代理人：Leon R. Yankwich,David G. O'Brien
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