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1-aryloxy-2,3,4,5-tetrahydro-3-benzazepine prepara

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专利名称:1-aryloxy-2,3,4,5-tetrahydro-3-benzazepine

preparation

发明人:Richard C. Effland,Joseph T. Klein,Larry Davis申请号:US07/513400申请日:19900423公开号:US05059688A公开日:19911022

摘要:The invention relates to 1-aryloxy-2,3,4,5-tetrahydro-3- benzazepines of theformula ##STR1## wherein Y is the same or different and is hydrogen and lower alkoxy; Xis hydrogen, halogen, lower alkyl, lower alkoxy, CF.sub.3, No.sub.2, CN and NH.sub.2 ; R ishydrogen, lower alkyl, cycloalkyllower alkyl, ##STR2## Ar lower alkyl of the formula##STR3## where Z is hydrogen, lower alkyl, lower alkoxy, halogen CF.sub.3, NO.sub. 2 andNH.sub.2 ; Aryloxy lower alkyl of the formula ##STR4## where Z is as previously defined;and an alkylene amine of the formula ##STR5## where R.sub.1 and R.sub.2 are the sameor different and are hydrogen and lower alkyl, n is an integer of 1 or 2; and thepharmaceutically acceptable acid addition salts thereof.

申请人:HOECHST-ROUSSEL PHARMACEUTICALS INC.

代理人:Tatsuya Ikeda

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